ALASONATI E., FABBRI B., FETTIG I., YARDIN C., DEL CASTILLO BUSTO M., RICHTER J., PHILIPP R. et FISICARO P., “Experimental design for TBT quantification by isotope dilution SPE-GC-ICP-MS under the European Water Framework Directive”, Talanta, 134, 2015, 576-586, DOI: 10.1016/j.talanta.2014.11.064.

CHEBIL S., FISICARO P. et MONOD M.-O., “Direct electrochemical synthesis and characterization of polypyrrole nano- and micro-snails”, Electrochimica Acta, 123, 2014, 527-534, DOI: 10.1016/j.electacta.2014.01.058.

CHEBIL S., FISICARO P., MONOD M.-O. et CHAMPION R., « Nouveau capteur de pH pour l’analyse de l’eau », Instrumentation & Interdisciplinarité – Capteurs Chimiques & Physiques, Editions EDP Sciences, 2014, 381-386, ISBN : 978-2-7598-1116-8.

DA G., GEHIN E., BEN-OTHMANE M., HAVET M., SOLLIEC C. et MOTZKUS C., “An experimental approach to measure particle deposition in large circular ventilation duc”, Environmental Science and Pollution Research, 22, 7, 2014, 4873-4880, DOI: 10.1007/s11356-014-2859-y.

ELORDUI-ZAPATARIETXE S., FETTIG I., PHILIPP R., GANTOIS F., LALÈRE B., SWART C., PETROV P., GOENAGA-INFANTE H., VANERMEN G., BOOM G. et EMTEBORG H., “Novel concepts for preparation of reference aterials as whole water samples for priority substances at ng.L^-1 level using model uspended particulate matter and humic”, Analytical and Bioanalytical Chemistry, 2014, DOI: 10.1007/s00216-014-8349-8.

HODOROABA V.-D., MOTZKUS C., MACÉ T. et VASLIN-REIMANN S., “Performance of High-Resolution SEM/EDX Systems Equipped with Transmission Mode (TSEM) for Imaging and Measurement of Size and Size Distribution of Spherical Nanoparticles”, Microscopy and Microanalysis, 20, 2, 2014, 602-612, DOI: 10.1017/S1431927614000014.

LARDY-FONTAN S., GUIGUES N., LALÈRE B. et VASLIN-REIMANN S., “Metrological needs for monitoring aquatic environments: From the demonstration of metrological traceability to the decision making process”, EPJ Web of Conferences, 77, 2014, DOI: 10.1051/epjconf/20147700011.

MOTZKUS C., GAIE-LEVREL F., AUSSET P., MAILLÉ M., BACCILE N., VASLIN-REIMANN S., IDRAC J., OSTER D., FISCHER N. et MACÉ T., “Impact of batch variability on physicochemical properties of manufactured TiO₂ and SiO₂ nanopowders”, Powder Technology, 267, 2014, 39-53, DOI: 10.1016/j.powtec.2014.06.055.

MOTZKUS C., GAIE-LEVREL F., MACE T., DELVALLEE A., DUCOURTIEUX S., MICHIELSEN N., BONDIGUEL S., GENSDARMES F., AUSSET P., MAILLE M. et VASLIN-REIMANN S., « Travaux prénormatifs sur la caractérisation de la taille des nanoparticules dans l’air : comparaison inter laboratoires avec des techniques de mesure directes et indirectes », Spectra Analyse, 296, 2014.

OSTER C., LABARRAQUE G. et FISICARO P., “Certification of a reference material of metal content in atmospheric particles loaded on filters”, Analytical and Bioanalytical Chemistry, 2014, DOI: 10.1007/s00216-014-8194-9.

STOICA D., BEN-ACHOUR M., SPITZER P., FISICARO P. et VASLIN-REIMANN S., « Mesures du pH de l’eau de mer : un défi d’actualité », Revue Française de Métrologie, 34, 2014, 23-30, DOI: 10.1051/rfm/2014006.

SWART C., ZAKEL S., FRANK C., FISICARO P. et GOENAGA-INFANTE H., “Metrological approach for the quantification of metalloproteins (EMRP project HLT05)”, EPJ Web of Conferences, 77, 2014, DOI: 10.1051/epjconf/20147700007.

WESTWOOD S., JOSEPHS R., GANTOIS F., LALÈRE B., SCHANTZ M.M. et SIEBER J.R., “Final report on key comparison CCQM-K55.c (L-(+)-Valine): Characterization of organic substances for chemical purity”, Metrologia, 51, 1A, 2014, DOI: 10.1088/0026-1394/51/1A/08010.

MACÉ T., “MACPoll intercomparison results for NO_x and SO₂ at EU limit values”, EURAMET-METCHEM Gas Sub-Committee, Teddington, Angleterre, 5 février 2014.

VASLIN-REIMANN S., « Améliorer la qualité des résultats de mesure: le rôle de la métrologie », Colloque DIM ANALYTICS 2014: Défis analytiques et société, Paris, France, 8 avril 2014.

FETTIG I., RICHTER J., PHILIPP R., PIECHOTTA C., ALASONATI E., FABBRI B. et FISICARO P., “Optimizing of a solid phase extraction method for tributyltin using a design of experiment and quantification with ID-GC-ICP-MS”, SETAC Europe 24th Annual Meeting, Bâle, Suisse, 11-15 mai 2014.

LARDY-FONTAN S., BRIEUDES V., LAVISON-BOMPARD G., CANDIDO P., COUTURIER G., BUDZINSKI H. et LALÈRE B., “Implementation of a complementary monitoring strategy to enable an efficient survey of pharmaceuticals in urban water cycle. A case study on the parisian area”, SETAC Europe 24th Annual Meeting, Bâle, Suisse, 11-15 mai 2014.

LARDY-FONTAN S., LAVISON-BOMPARD G., BRIEUDES V., CANDIDO P., COUTURIER G., LALÈRE B. et BUDZINSKI H., “From the initial monitoring to thedevelopment of a reference method. A case study on pharmaceuticals residues on the Paris area”, SETAC Europe 24th Annual Meeting, Bâle, Suisse, 11-15 mai 2014.

KAISER C., SUTOUR CH. et MACÉ T., “Development of a quad quantum cascade laser spectrometer for simultaneous detection of NO, NO₂, SO₂ and CO at nmol/mol levels, data processing and associated uncertainties”, MacPoll final conference, Delft, Pays-Bas, 13-14 mai 2014.

MACÉ T., “Validation of the methods used for generating standard gas mixtures by an interlaboratory comparison for NO, NO₂ and SO₂ at limit values”, MacPoll final conference, Delft, Pays-Bas, 13-14 mai 2014.

FISICARO P., « Améliorer la qualité des résultats de mesure : le rôle du laboratoire national de métrologie », Spectr'Atom 2014, Pau, France, 20-23 mai 2014.

PALOS M., DEL CASTILLO E., PANNIER F. et FISICARO P., « Détermination des métalloprotéines par DI-ICPMS afin d'assurer la traçabilité métrologique en biochimie clinique », Spectr'Atom 2014, Pau, France, 20-23 mai 2014.

BROS P., BARTHELEMY N., VIALARET J., BECHER F., GABELLE A., DELATOUR V., LEHMANN S. et HIRTZ C., “Mass spectrometry quantification of human CSF Tau protein in sub-nanogram/milliliters range”, 12^e journée de l’Ecole Doctorale CBS2, Montpellier, France, Mai 2014.

BROS P., BARTHELEMY N., VIALARET J., BECHER F., GABELLE A., DELATOUR V., LEHMANN S. et HIRTZ C., “Comparison of PRM and SRM analytical performances for the quantification of Tau protein in human C”, SMAP 2014 : Congrès français de Spectrométrie de Masse et d’Analyse Protéomique, Lyon, France, juin 2014.

ALASONATI E., FETTIG I., FABBRI B., YARDIN C., RINCEL A., DEL CASTILLO M.E., PANAYOT P., PHILIPP R. et FISICARO P., “TBT quantification by isotope dilution mass spectrometry under the European water framework Directive”, International Symposium on Environmental Analytical Chemistry (ISEAC38), Lausanne, Suisse, 16-19 juin 2014.

KOTZEVA B., ALASONATI E., PHILIPP R. et FISICARO P., “Development of analytical method for TBT speciation in coastal lyes and sea water (Pomorie Lake, Black Sea, Bulgaria)”, International Symposium on Environmental Analytical Chemistry (ISEAC38), Lausanne, Suisse, 16-19 juin 2014.

LARDY-FONTAN S., LAVISON-BOMPARD G., BRIEUDES V., CANDIDO P., COUTURIER G., LALÈRE B. et BUDZINSKI H., “Measurement uncertainty in water monitoring: contribution of both laboratory and sampling uncertainties. A cases study on pharmaceuticals in the Seine River (France)”, International Symposium on Environmental Analytical Chemistry (ISEAC38), Lausanne, Suisse, 16-19 juin 2014.

LAVISON-BOMPARD G., LARDY-FONTAN S., BRIEUDES V., CANDIDO P., JOYEUX M., LALÈRE B. et BUDZINSKI H., “Implementation of complementary monitoring strategies for an effective survey of psychotropic drugs and metabolites in drinking water treatment plants in the parisian area”, International Symposium on Environmental Analytical Chemistry (ISEAC38), Lausanne, Suisse, 16-19 juin 2014.

RAAB A., FELDMAN J., GOENAFA-INFANTE H., NUNNEZ S., DEL CASTILLO M.E., FISICARO P., KONOPKA A. et LEHMANN W.-D., “Determination of Selenoprotein P in human serum by isotope dilution ICP-MS”, THE BNASS / TraceSpec Tandem Conference, Aberdeen, Royaume-Uni, 31 août-04 sept. 2014.

VASLIN-REIMANN S. et DELATOUR V., « Quelles recherches pour progresser dans la maîtrise des analyses? », JT du CFM, Paris, France, 23 septembre 2014.

LAVISON-BOMPARD G., BRIEUDES V., LARDY-FONTAN S., CANDIDO P., COUTURIER G., LALERE B., JOYEUX M. et BUDZINSKI H., « Deux stratégies d’échantillonnage pour la surveillance de la qualité des eaux des usines de potabilisation d’Eau de Paris vis-à-vis de substances pharmaceutiques par des résidus médicamenteux », JIE 2014, Poitiers, France, 4-6 novembre 2014.

VASLIN-REIMANN S. et LALERE B., « Traçabilité des analyses Chimiques », JT du CFM, Paris, France, 10 décembre 2014.

ALASONATI E., DEL CASTILLO M.E., LABARRAQUE G. et FISICARO P., “Speciation analyses: applications to metalloproteins and persistent pollutants”, CETAMA GT 12 – ICP/MS, Les Renadières, France.

ALASONATI E., FABBRI B., FETTIG I., YARDIN C., DEL CASTILLO BUSTO M.-E., RICHTER J., PHILIPP R. et FISICARO P., “Experimental design for TBT quantification by isotope dilution SPE_GC_ICP_MS under the European water framework directive”, Talanta, 134, 2015, 576-586, DOI: 10.1016/j.talanta.2014.11.064.

BARBE J., BOINEAU F., MACÉ T. et OTAL P., “Development of a gas micro flow transfer standard”, Flow measurement & instrumentation, numéro spécial, 44, 2015, 43-50, DOI: 10.1016/j.flowmeasinst.2014.11.011.

BENKOULA S., SUBLEMONTIER O., PATANEN M., NICOLAS C., SIROTTI F., NAITABDI A., GAIE-LEVREL F., ANTONSSON E., AUREAU D., OUF F-X., WADA S-I., ETCHEBERRY A., UEDA K. et MIRON C., “Water adsorption on TiO₂ surfaces probed by soft X-ray spectroscopies: Bulk materials vs. isolated nanoparticles”, Scientific Reports, 5, 15088, 2015, DOI: 10.1038/srep15088.

BREWER P.J., PANAGOULIA D., BROWN R.J.C., TROMANS A., REYES A., ARCE M., SPITZER P., FISICARO P. et STOICA D., “International comparison on Ag|AgCl electrodes for pH measurement”, Measurement, 66, 2015, 131-138, DOI: 10.1016/j.measurement.2015.01.029.

BROS P., VIALARET J., BARTHELEMY N., DELATOUR V., GABELLE A., LEHMANN S. et HIRTZ C., “Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry”, Frontiers in Neuroscience, 9, 2015, 302, 1-8, DOI: 10.3389/fnins.2015.00302.

BROS P., DELATOUR V., VIALARET J., LALERE B., BARTHELEMY N., GABELLE A., LEHMANN S. et HIRTZ C., “Quantitative detection of amyloidbetapeptides by mass spectrometry: state of the art and clinical applications”, Clinical Chemistry and Laboratory Medicine (CCLM), 53, 10, 2015, 1483-1493, DOI: 10.1515/cclm-2015-099.

BROWN R.J.C., BREWER P.J., ENT H., FISICARO P., HORVAT M., KIM K-H. et QUETEL C.R., “Who should take responsibility for decisions on internationally recommended datasets? The case of the mass concentration of mercury in air at saturation”, Metrologia, 52, 5, 2015, L25-L30, DOI: 10.1088/0026-1394/52/5/L25.

CABILLIC J., FALLOT C., HEIN S., LALERE B. et PHILIPP R., « Développement et validation d’une méthode de référence pour l’analyse des HAP dans l’eau totale dans le contexte de la DCE », Revue française de métrologie, 40, 2015, 3-12, DOI: 10.1051/rfm/2015014.

CHIVAS-JOLY C., LONGUET C., MOTZKUS C. et LOPEZ CUESTA J-M., “Influence of the composition of PMMA nanocomposites on gaseous effluents emitted during combustion”, Polymer Degradation and Stability, 113, 2015, 197-207, DOI: 10.1016/j.polymdegradstab.2014.11.015.

DELATOUR V. et FAVRE G., « Le LNE CRM bio 101a est désormais reconnu comme matériau de référence d'ordre supérieur par le JCTLM », Spectra biologie, 217, 2015, 37.

ELORDUI-ZAPATARIETXE S., FETTIG I., PHILIPP R., GANTOIS F., LALERE B., SWART C., PETROV P., GOENAGA-INFANTE H., VANERMEN G., BOOM G. et EMTEBORG H., “Novel concepts for preparation of reference materials as whole water samples for priority substances at nanogram-per-liter level using model suspended particulate matter and humic acids”, Analytical and Bioanalytical Chemistry, 407, 11, 2015, 3055-3067, DOI: 10.1007/s00216-014-8349-8.

ELORDUI-ZAPATARIETXE S., FETTIG I., RICHTER J., PHILIPP R., GANTOIS F., LALERE B., SWART C. et EMTEBORG H., “Interaction of 15 priority substances for water monitoring at ng L21 levels with glass, aluminium and fluorinated polyethylene bottles for the containment of water reference materials”, Accreditation and quality assurance, 20, 6, 2015, 447-455, DOI: 10.1007/s00769-015-1150-3.

GAIE-LEVREL F., MOTZKUS C., MACE T. et VASLIN-REIMANN S., « Développement d’une méthode d’étalonnage pour les instruments de mesure de concentration massique particulaire dans l’air ambiant », Revue française de métrologie, 38, 2015, 11-18, DOI: 10.1051/rfm/2015006.

GEHIN E., BEN-OTHMANE M., HAVET M., SOLLIEC C. et MOTZKUS C., “An experimental approach to measure particle deposition in large circular ventilation ducts”, Environmental Science and Pollution Research international, 22, 7, 2015, 4873-4880.

GONZALEZ-ANTUNA A., RODRIGUEZ-GONZALE Z.P., OHLENDORF R., HENRION A., DELATOUR V. et GARCIA ALONSO J.I., “Determination of Cystatin C in human serum by isotope dilution mass spectrometry using mass overlapping peptides”, Journal of Proteomics, 112, 2015, 141-155, DOI: 10.1016/j.jprot.2014.09.005.

GUILLAUME E. et SARAGOZA L., “Application of FTIR analyzers to fire gases-Progress in apparatus and method validation for quantitative analysis”, Fire and Materials 2015 - 14th International Conference and Exhibition, San Francisco, Etats-Unis d’amérique, 162-174, 2-4 février 2015.

GUILLAUME E., SARAGOZA L., WAKATSUKI K. et BLOMQVIST P., “Effect of gas cell pressure in FTIR analysis of fire effluents”, Fire and Materials, 39, 7, 2015, 675-684, DOI: 10.1002/fam.2273.

HIOKI A., ASAKAI T., MAKSIMOV I., SUZUKI T., MIURA T. et FISICARO P., “Report of the key comparison APMP.QM-K19 - APMP comparison on pH measurement of borate buffer”, Metrologia, 52, Techn. suppl., 2015, 08003, DOI: 10.1088/0026-1394/52/1A/08003.

LABARRAQUE G., OSTER C., FISICARO P., MEYER C., VOGL J., NOORDMANN J., RIENITZ O., RICCOBONO F. et DONET S., “Reference measurement procedures for the quantification of platinum group elements (PGEs) from automotive exhaust emissions”, International journal of environmental analytical chemistry, 95, 9, 2015, 777-789, DOI: 10.1080/03067319.2015.1058931.

MIEGE C., MAZZELLA N., ALLAN I., DULIO V., SMEDES F., TIXIER C., VERMEIRSSEN E., BRANT J., O'TOOLE S., BUDZINSKI H., GHESTEM J-P., STAUB P-F., LARDY-FONTAN S., GONZALEZ J-L., COQUERY M. et VRANA B., “Position paper on passive sampling techniques for the monitoring of contaminants in the aquatic environment - Achievements to date and perspectives”, Trends in Environmental Analytical Chemistry, 8, 2015, 20-26, DOI: 10.1016/j.teac.2015.07.001.

OSTER C., LABARRAQUE G. et FISICARO P., “Certification of a reference material of metal content in atmospheric particles deposited on filters”, Analytical and Bioanalytical Chemistry, 407, 11, 2015, 3035-3043, DOI: 10.1007/s00216-014-8194-9.

OUNOUGHENE G., LE BIHAN O., CHIVAS-JOLY C., MOTZKUS C., LONGUET C., DEBRAY B., JOUBERT A., LE COQ L. et LOPEZ CUESTA J.-M., “Behavior and Fate of Halloysite Nanotubes (HNTs) When Incinerating PA6/HNTs Nanocomposite”, Environmental Science and Technology, 49, 9, 2015, 5450-5457, DOI: 10.1021/es505674j.

PALOS M., DEL CASTILLO, BUSTO M.E., HATTCHOUEL J.-M., PANNIER F., FISICARO P. et VASLIN-REIMANN S., « Développement d’une méthode primaire pour la détermination du fer total dans du sérum », Revue française de métrologie, 40, 2015, 41-50, DOI: 10.1051/rfm/2015015.

YVER KWOK C., LAURENT O., GUEMRI A., PHILIPPON C., WASTINE B. et KAISER C., “Comprehensive laboratory and field testing of cavity ring-down spectroscopy analyzers measuring H₂O, CO₂, CH₄ and CO”, Atmospheric Meas. Techniques, 8, 9, 2015, 3867-3892, DOI: 10.5194/amt-8-3867-2015.

GUILLAUME E. et SARAGOZA L., “Application of FTIR analyzers to fire gases-Progress in apparatus and method validation for quantitative analysis”, Fire and Materials 2015 - 14th International Conference and Exhibition, San Francisco, Etats-Unis d’amérique, 162-174, 2-4 février 2015.

DEL CASTILLO BUSTO M.E., OSTER C., NUNEZ S., RAAB A., KONOPKA A., LEHMANN W.-D., GOENAGA-INFANTE H. et FISICARO P., “Comparison of different quantification methods for the determination of selenoproteins in human serum: Focus on selenoprotein P”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

FETTIG I., PIECHOTTA C., ALASONATI E., SWART C., KOSCHORRECK J. et FISICARO P., “Traceability for mercury measurements”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

FISICARO P., ALASONATI E., ENT H., SWART C., GOENAGA-INFANTE H. et HORVAT M., “Development of a European metrological infrastructure for mercury measurements”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

KONOPKA A., WINTER D., KONOPKAW., DEL CASTILLO BUSTO M.E., NUNEZ S., GOENAGA-INFANTE H., FISICARO P., BULSKA E. et LEHMANN W.-D., “Novel full-length [Sec-to-Cys]selenoprotein standards for human selenoprotein P and glutathione peroxidase 3 for quantitative proteomics”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

SCHÜTZE M., WERIAN A., SWART C., RIENITZ O., BIESTER H., FISICARO P. et GOENAGA-INFANTE H., “Traceability for speciation of mercury in water and isotopic ratio measurements”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

SWART C., TOKMAN N., RAAB A., JAKUBOWKS, N., DEL CASTILLO M.-E., GOENAGA-INFANTE H., KONOPKA A., ZAKEL S. et BERNEVIC B, “Development of reference measurement procedures for metalloproteins (EMRP HLT 05 Metallomics)”, European Winter Conference on Plasma Spectrochemistry 2015 (EWCPS 2015), Münster, Allemagne, 22-26 février 2015.

DELATOUR V., « Evaluation de la justesse des méthodes de dosage de biomarqueurs en biochimie clinique : importance de la commutabilité et des méthodes de référence », Séminaire « Métrologie en biologie médicale », Hôpital Européen Georges Pompidou, Paris, France, 6 mars 2015.

CLOUET FORAISON N., GAIE-LEVREL F. et DELATOUR V., « Application de l’analyse par mobilité différentielle à la caractérisation de bio-nanoparticules », 1^er congrès francophone de l’AFSEP, Paris, France, 31 mars - 2 avril 2015.

MACÉ T., GAIE-LEVREL F. et MOTZKUS C., “Overview of LNE's activities led in aerosol metrology”, Particulate Workshop (BIPM), Sèvres, France, 15 avril 2015.

BROS P., DELABY C., DELATOUR V., MOULINIER A., CAZALS G., VIALARET J., LEHMANN S. et HIRTZ C., “Towards a reference method for absolute quantification of hepcidin-25 in serum by mass spectrometry”, Congrès Euromedlab/IFCC, Paris, France, 21-25 juin 2015.

CLOUET-FORAISON N., GAIE-LEVREL F., KAMMEL M., DIVIETO C., PARKS H. et DELATOUR V., “Standardization in advanced Lipoprotein testing: The BioSITrace project”, Congrès Euromedlab/IFCC, Paris, France, 21-25 juin 2015.

FISICARO P., ENT H., SWART C., DUNN P. et HORVAT M., “Development of a metrological infrastructure for mercury measurements”, ICMGP 2015 Korea, Jeju, Corée, 22-26 juin 2015.

DEL CASTILLO BUSTO M.E., OSTER C., NUNEZ S., RAAB A., KONOPKA A., LEHMANN W.D., GOENAGA-INFANTE H. et FISICARO P., “Isotope dilution mass spectrometry as a traceable tool to assess selenium status in humans”, Euromedlab Satellite meeting “State of the art in the biology of trace elements and vitamins”, Paris, France, 26-27 juin 2015.

PALOS M., DEL CASTILLO BUSTO M.E., PANNIER F., SWART C., BRAUCKMANN C. et FISICARO P., “Reference methods for iron and haemoglobin by isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-MS) to assess metrological traceability in clinical biochemistry”, Euromedlab Satellite meeting “State of the art in the biology of trace elements and vitamins”, Paris, France, 26-27 juin 2015.

BRIEUDES V., LARDY-FONTAN S., LALERE B., VASLIN-REIMANN S. et BUDZINSKI H., “Method validation and uncertainties evaluation for more reliable measurements of drug residues in the environment: a case study on the Seine river”, Workshop: Mediterranean Sea Region Countries Mass Spectrometry Workshop (MEDMS III), Athènes, Grèce, 28 juin - 2 juillet 2015.

MACÉ T., “The national laboratory for air quality monitoring (LCSQA): a 25 years feedback, The third International Conference on Environmental Specimen Banks, Nancy, France, 30 juin - 1^er juillet 2015.

PALOS M., DEL CASTILLO BUSTO M.E., BRAUCKMANN C., SWART C., POTIN-GAUTIER M., PANNIER F. et FISICARO P., “Reference methods for total haemoglobin by isotope dilution inductively coupled plasma mass spectrometry to assess metrological traceability in clinical biochemistry”, Euroanalysis 2015, Bordeaux, France, 6-10 septembre 2015.

DESENFANT M., ALLARD A., LALERE B., LARDY-FONTAN S., LE DIOURON V., LEPOT B. et ZIEGLER E., « Comparaison de différentes stratégies d'évaluation de la performance dans les essais d'aptitude par comparaison interlaboratoire », 17^e Congrès international de métrologie, Paris, France, 21-24 sept. 2015.

FISICARO P., ENT H., SWART C., DUNN P. et HORVAT M., “Traceability for mercury measurements”, 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015 DOI: 10.1051/metrology/20150007001.

GAIE-LEVREL F. , MOTZKUS C. et MACÉ T., “Development of a calibration method for on-line analyzer of atmospheric particle mass concentrations”, 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015, DOI: 10.1051/metrology/20150007002.

GAIE-LEVREL F., MOTZKUS C. et MACÉ T., “Metrological characterisation of the size distribution of airborne nanoparticles generated from nanomaterials in the form of colloidal suspension”, 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015.

LARDY-FONTAN S., “Development and implementation of a DI-MS based method with full uncertainty estimate to achieve measurement of pharmaceutical residus in natural waters”, 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015, DOI: 10.1051/metrology/20150005001.

LARDY-FONTAN S., CHATELLIER C., LESTREMAU F., LALERE B. et STRUB M-P., “Reliability of organic compounds measurement in enviromental monitoring. The key role of analytical standard substance. A study case on alkylphenols”, 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015, DOI: 10.1051/metrology/20150007010.

PALOS M., DEL CASTILLO BUSTO M.E., PANNIER F., SWART C., BRAUCKMANN C. et FISICARO P., « Détermination de l’hémoglobine totale par dilution isotopique ICP-MS afin d’assurer la traçabilité métrologique en biochimie clinique », 17^e Congrès international de métrologie, Paris, France, 21-24 septembre 2015, DOI: 10.1051/metrology/20150009005.

LARDY-FONTAN S. et al., “Metrology applied to the survey of pharmaceutical residues in water for a better protection of consumers”, Workshop: “Food metrology: Approaches and tools for measuring food quality”, Milan, Italie, 9 octobre 2015.

SWART C., GLEITZMANN J., TOKMAN N., RAAB A., DEL CASTILLO BUSTO M.E., BRAUCKMANN C., ZAKEL S., ARSENE C.-G., FRANK C. et NEUKAMMER J., “Candidate reference measurement procedures for metalloproteins for the characterisation of future reference materials”, 14^th International Symposium on Biological and Environmental Reference Materials (BERM 14), Maryland, États-Unis, 11-15 octobre 2015.

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DELABY S., GAIE-LEVREL F., WIART M. et BENCSIK A., “Impact on the nervous system of particles released from nanocomposite materials under stress use (Release_NanoTox)”, European Nanomedicine Meeting (ENM 2015), Grenoble, France, 7-9 décembre 2015.

Air quality is a major social issue. Among the many compounds that could be harmful for Human health, Volatile Organic Compounds (VOCs) belong to the most monitored and regulated pollutants. In France, the monitoring of VOCs in ambient air is carried out by sampling air onto activated carbon cartridges during a given period (7 or 14 days) by the “Associations Agréées de Surveillance de la Qualité de l’Air” (AASQA). This method consists of two parts: sampling and analysis. To ensure the reliability of their measurement results, laboratories must guarantee the traceability of their analysis and validate their analytical protocols: this can be done by the use of Certified matrix Reference Materials (CRMs). However, in France, no reference materials are available for the measurement of VOCs in air onto sorbent tubes. Therefore, LNE developed a system for loading benzene, from a gaseous reference material onto Carbopack X tubes. These CRMs could be used for the calibration of analytical systems and for the evaluation of analytical laboratories. After this development phase, LNE has organized a proficiency testing between three expert laboratories, based on the implementation of these materials: it shows no significant differences between analyzed masses and loaded masses for each participating laboratories.

Le LNE a développé une technique de mesure des propriétés radiatives infrarouges de liquides volatils. Un réflectomètre est utilisé pour la mesure du facteur de réflexion directionnelle hémisphérique spectrale (0,8 µm à 14 µm) et un spectromètre à transformée de Fourier est utilisé pour la mesure de la transmission spectrale régulière (1 µm à 25 µm). Pour les liquides volatils, une cellule étanche avec deux hublots a été construite. Des modèles ont été établis pour calculer l’indice de réfraction complexe du liquide à partir des résultats de mesure de la réflexion et de la transmission spectrale sur la cellule remplie de liquide. Les résultats ont été validés pour l’eau par comparaison à des valeurs trouvées dans la documentation scientifique.

In 2008, creatinine measurement was the fifth most common analysis in laboratory medicine in France. Creatinine is the main biomarker used for the diagnosis, follow-up and monitoring of chronic kidney disease, a serious pathology that affects approximately three million subjects in France. To avoid the evolution of chronic kidney disease to end stage renal disease, it is essential to have reliable creatinine measurements in order to allow efficient and early diagnosis. To address these challenges, the contribution of metrology is essential to improve clinical measurements reliability and comparability. First, reference methods are necessary to assign reference values to calibration materials. This is the first step to establish the metrological traceability of results to the International system of units (SI) and lead to the standardization of medical analysis. Second, reference methods are essential to assign reference values to quality control samples, providing suitable tools for assessing the accuracy of routine methods and those used by in vitro diagnostic products manufacturers.

LNE is developing a MEtrological ChARacterization of Nanomaterials (CARMEN) platform to offer a complete supply of main parameter measurements characterizing a nano-object (size, shape, polydispersity, agglomeration/aggregation state, surface charges, specific charges. . . ). Other physical properties such local electrical measurements will be able to be performed on nanodevices. This platform aims to establish tracability routes, define measurement protocols and sampling methods. The uncertainties associated with measurements will offer to users an optimum confidence level. Instrumentation is put in a clean room within a controlled environment (temperature, humidity, vibration. . . ). Thanks to this platform, LNE will be able to help manufacturers and laboratories to meet to the governmental requests concerning the mandatory declaration of nanosubstances as described in the French decree number 2012-232, dated the 17th on February, 2012 (JORF number 0043 on 19th February 2012). Furthermore, this platform will make it possible to support the teams involved in the toxicological investigations linked to nanomaterials.

Day after day, new applications using manufactured nanoparticles appear in industry. To evaluate the occupational risk associated to nanoparticles, it is important to have reliable, accurate and standardized measurement methods. It is therefore necessary to work on pre-normalization projects to develop reference methods to characterize the number and the size distribution of airborne nanoparticles. The aim of this pre-normalization project is to develop characterization methods for airborne nanoparticles that include all the measurement chain (sampling, analysis, data treatments, etc.) which will be traceable, adequate and accurate: this project includes the estimation of the uncertainties on the measurements. This presented study, first step of this project, describes the generation and the characterization of SiO₂ airborne nanoparticles from a liquid manufactured suspension. Experiments have been performed in order to study the stability and the repeatability of the generation protocol of SiO₂ airborne nanoparticles by measuring their count size distributions with a Scanning Mobility Particle Sizer (SMPS).

pH measurements of seawater are suffering of a lack of spatiotemporal compatibility and comparability. The present paper makes an analysis of the current state of art of seawater pH measurement. The theoretical problemes, such as the definition of the activity coefficient, and practical problemes related especially to the complex matrix are pointed out. The necessary actions to overcome theses difficulties are also described. They are part of an European Joint Research Project entituled “Metrology for the salinity and ocean acidification” and funded by EMRP. Some preliminary results obtained for a saline solution containing only NaCl are presented in order to show the influence of the matrix on the experimentally obtained acidity functions.

This work presents the development of a reference method by ICP-MS for the determination of iron in serum. To ensure the metrological traceability of the results, isotope dilution associated with ICP-MS (ID-ICP-MS) has been applied, which has the potential to be a primary measurement procedure. Method validation has been demonstrated through the use of a certified reference material (SRM 1598a) and the participation in an international comparison between National Metrology Institutes (BIPM-CCQM K107). The validated method is now available to support clinical laboratories in the evaluation of their measurement capabilities and for quality assurance and quality control programmes. In fact, this ID-ICP-MS method can be used to certify reference materials or to assign reference values to samples used in proficiency testing schemes. The feasibility has been tested on two unknown samples, i.e. BCR^® -637, IRMM sample and an ANSM B17 sample (a material distributed during a National Quality Control programme).

To ensure the water quality in Europe, the European Commission asked the member states to provide comparable and traceable measurement results for the analysis of critical pollutants. Considering the increasing environmental challenges, the contribution of metrology is necessary both for the improvement of analysis reliability and the comparability of results. For this reason the European research project Euramet/EMRP/ENV08 “Traceable measurements for monitoring critical pollutants under the European Water Framework Directive (WFD-2000/60/EC)”, funded by the EMRP, aimed to provide the elements for the development of a metrological basis. The project develops primary reference methods enabling the analysis of priority hazardous substances in order to meet the WFD requirements in terms of performance levels (limit of quantification and uncertainties). Polycyclic aromatic hydrocarbons (PAHs) – priority hazardous substances for which no DCE compatible methods exist – are among the three families of pollutants targeted by the project. This paper tackles the development and validation of the PAH analysis method on whole water samples. The method that best meets the requirements of the WFD in terms of level of concentration and uncertainty is the solid phase extraction (SPE) method with SPE-disks, followed by isotope dilution analysis combined with gas chromatography mass spectrometry (ID-GC/MS).